5 mg/kg/dose (Max: 20 mg) PRN The 8-mg dose is taken again 8 hours after the first dose
Prevention and treatment of chemotherapy- and radiotherapy-induced nausea and vomiting— (follow-on dose based on body surface area) By mouth
Acetic acid: Pediatric drug information
In patients with severe hepatic impairment (Child-Pugh score of 10 or greater), do not exceed a total daily dose of 8 mg [see Use in Specific Populations
Verywell / Nusha Ashjaee Uses of Zofran for Kids Zofran is approved for the prevention of nausea and vomiting in people undergoing chemotherapy or radiation
Ondansetron may be given by mouth as a liquid, pill, or tablet; or in a vein (IV)
Oral ondansetron comes as a tablet, an orally disintegrating tablet (ODT), and an oral
10 - 15 mg/kg/dose Q4-6 (Max: < 2 years: 60
When administered orally, it is rapidly absorbed by the gastrointestinal tract, achieving peak
04 mg 0
1
15 mg/kg doses, up to a maximum of 16 mg per dose, infused intravenously over 15 minutes
Take this medication exactly as directed
There are few studies of associations of house dust mites with childhood asthma, wheeze, rhinitis and eczema
The intervention: CAU plus ondansetron
Oral rehydration therapy with oral rehydration solution was initiated 15 minutes after ondansetron or placebo
12 to 17 years of age: 8 mg administered 30 minutes before the start of chemotherapy, with a subsequent 8-mg dose 8 hours after the first dose
A single oral dose of ondansetron has been shown to reduce the risk of recurrent vomiting, the need for intravenous fluids, and hospital
15 mg/kg per dose, with a maximum of 16 mg per dose
In patients with severe hepatic impairment (Child-Pugh score of 10 or greater), The initial dose of ZOFRAN injection ranged from 0
Ondansetron works in the stomach to block the signals to the brain that cause nausea and vomiting
Feeling sleepy
To determine if higher doses of oral ondansetron are associated with greater efficacy or side effects
• Actual convictions come from studies evaluating one and more than one dose of the drug
6, 10 The first compared oral ondansetron with placebo and oral rehydration for pediatric AGE in a randomized, double-blind trial involving 145 patients who had vomited at least 5 times in
risk of QT prolongation, cardiac arrhythmias (mechanism unknown; additive effects) cisapride
In patients with severe hepatic impairment (Child-Pugh score of 10 or greater), The initial dose of ZOFRAN injection ranged from 0
075mg/kg/dose Maximum dose being 4mg for children 2-11y and 8 mg/dose in children greater than 12 years of age
Use a single dose of oral ondansetron in combination with oral rehydration for patients with dehydration, nausea, and vomiting
15 mg/kg up to 4 mg) is the most used antiemetic and is considered the “gold standard” in PONV management
Age 2 to 5 Years: 12
10 ORT should begin or resume in the 15 to 30 minutes following administration